By now, you know someone who is taking one of the new “wonder” drugs like Ozempic (semaglutide) or Zepbound/Mounjaro (tirzepatide). These medications are for diabetes but are being used off-label for weight loss. The prescription, Wegovy, is the actual medication approved for weight loss as it comes in higher doses than then other counterparts.
There are more and more studies touting the benefits of these medications including a recent one showing a reversal of liver fibrosis! However, there are some side-effects that you should be aware of. READ on to make sure you are aware….
While known potential serious side-effects include issues with your liver, kidneys, pancreas and thyroid, there are more common side-effects that include gastroparesis which is slowing of the emptying of food and constipation, nausea and in some cases diarrhea. Recently, the mental health side-effects of these drugs are just now hitting the radar.
Wegovy is the actual weight loss drug and is in higher concentrations than the other diabetes counterparts like semaglutide or tirzepatide. It has manufacturer label stating “suicidal behavior and ideation have been reported in clinical trials with other weight management products,” and patients treated with Wegovy should be monitored “for the emergence of worsening of depression, suicidal thoughts or behavior, and/or any unusual changes in mood or behavior.” It is not recommended to use Wegovy if you have a history of suicidal ideation or attempts.
What about semaglutide or tirzepatide? For now, there are no warnings on the label regarding mental health concerns but a recent study looking at chat groups for these medications on social media have shed some light of some potential issues.
The following symptoms were reported:
- Insomnia
- Depression
- Mental health issues in general (mood changes, anxiety, etc)
Not all reports were negative as some reported improved control of addictive behaviors as well as improved mood!
The take home message is if you are taking any one of these medications and are starting to feel blue, have sleep issues or higher anxiety you might consider stopping the medication (with the help of your provider) and see if your symptoms improve!
To your health,
Laura
